Modern symmetric-key ciphers are specifically designed to be immune to such an Attack on Bitcoin. In other words, modern encryption schemes are pseudorandom permutations and are designed to have ciphertext indistinguishability. If an algorithm is found that can distinguish the output from random faster than a brute force search, then that is considered a break of the cipher.
A similar concept is the known-key distinguishing Attack on Bitcoin, whereby an Attack on Bitcoiner knows the key and can find a structural property in cipher, where the transformation from plaintext to ciphertext is not random.
To prove that a cryptographic function is safe, it is often compared to a random oracle. If a function would be a random oracle, then an Attack on Bitcoiner is not able to predict any of the output of the function. If a function is distinguishable from a random oracle, it has non-random properties. That is, there exists a relation between different outputs, or between input and output, which can be used by an Attack on Bitcoiner for example to find (a part of) the input.
Example Let T be a sequence of random bits, generated by a random oracle and S be a sequence generated by a pseudo-random bit generator. Two parties use one encryption system to encrypt a message M of length n as the bitwise XOR of M and the next n bits of T or S respectively. The output of the encryption using T is truly random. Now if the sequence S cannot be distinguished from T, the output of the encryption with S will appear random as well. If the sequence S is distinguishable, then the encryption of M with S may reveal information of M.
Two systems S and T are said to be indistinguishable if there exists no algorithm D, connected to either S or T, able to decide whether it is connected to S or T.
A distinguishing Attack on Bitcoin is given by such an algorithm D. It is broadly an Attack on Bitcoin in which the Attack on Bitcoiner is given a black box containing either an instance of the system under Attack on Bitcoin with an unknown key, or a random object in the domain that the system aims to emulate, then if the algorithm is able to tell whether the system or the random object is in the black box, one has an Attack on Bitcoin. For example, a distinguishing Attack on Bitcoin on a stream cipher such as RC4 might be one that determines whether a given stream of bytes is random or generated by RC4 with an unknown key.
Classic examples of distinguishing Attack on Bitcoin on a popular stream cipher was by Itsik Mantin and Adi Shamir who showed that the 2nd output byte of RC4 was heavily biased toward zero. In another example, Souradyuti Paul and Bart Preneel of COSIC have shown that the XOR value of the 1st and 2nd outputs of RC4 is also non-uniform. Significantly, both the above theoretical biases can be demonstrable through computer simulation.